Integrated analysis of breast cancer cell lines reveals unique signaling pathways

16 Sep 2014 | Publications | Contributor(s): Laura M Heiser, Nicholas J Wang, Carolyn L Talcott, Keith R Laderoute, Merrill Knapp, Yinghui Guan, Zhi Hu, Safiyyah Ziyad, Barbara L Weber, Sylvie Laquerre, Jeffrey R Jackson, Richard F Wooster, Wen Lin Kuo, Joe W Gray, Paul T Spellman

AbstractBackgroundCancer is a heterogeneous disease resulting from the accumulation of genetic defects that negatively impact control of cell division, motility, adhesion and apoptosis. Deregulation in signaling along the EgfR-MAPK pathway is common in breast cancer, though the manner in which...

Integrative Cancer Biology Program Datasets

26 Apr 2016 | Series | Contributor(s): Jonathan Bistline, Michael Reich

The NCI-ICBP promotes an integrative/systems approach to the study of cancer biology. The Program encourages scientists to study cancer as a complex biological system. Information gained from these studies are used to build reliable and testable predictive computation models of cancer processes...

LBL ICBP50 integrative genomic data

13 Nov 2014 | Downloads | Contributor(s): Joe Gray, Jonathan Bistline

From Joe Gray, Lawrence Berkeley National Laboratory.  There are seventeen (17) files in this study: Affymetrix U133A gene expression data (icbp_u133a.gct) Affymetrix U133A gene expression data (ICBP_U133a.zip) Affymetrix splice junction exon-exon data (ICBP_Junction.zip) Affymetrix...

NCI Alliance for Nanotechnology in Cancer, and caNanoLab: A Data Repository for Cancer Nanomedicines

27 Nov 2018 | Presentations | Contributor(s): Luisa Russell, Mervi Heiskanen

Nano WG presentation November15, 2018 NCI Alliance for Nanotechnology in Cancer –Structure–Achievements–Scientific FocuscaNanoLab–Intro to Platform–Data Curation–User Statistics–Future Directions

NCI Standard CRFs

15 Mar 2014 | Teaching Materials | Contributor(s): Denise Warzel, Ann Christine Catlin, Sumudinie fernando

Working in conjunction with NCI has developed a collection of Standard Case Report Forms (CRFs) for use in developing new protocols. The project and its status are described here. The reuse of sections from standard CRFs helps to ensure that data collected in different studies is compatible and...

October 2021 CWIG Webinar Slides - Arun Isaac

27 Dec 2021 | Downloads | Contributor(s): Alan Zheng

October 2021 CWIG Webinar Slides - Pjotr Prins

27 Dec 2021 | Downloads | Contributor(s): Alan Zheng

Patient Stories

30 Nov 2015 | Teaching Materials | Contributor(s): Diane Townsel

Beaumont’s Patient videos: is the story of five patients that have participated in clinical research or have been a part of a bio-specimen study. The videos tell the unique stories of our patients and how our Cancer Clinical Trials staff build relationships with our patients and guide them...

Performance Status Scoring : a standards portal resource

15 Mar 2014 | Teaching Materials | Contributor(s): Ann Christine Catlin, Sumudinie fernando, Denise Warzel, Angela Kummerow

The scoring scale used may depend on patient population, disease, study goals and other criteria. Many definitions of the scale scoring do not match the standard.What is Performance Status?Performance status attempts to quantify the general well-being of cancer and other patients. The score...

Por Nuestras Hijas/For Our Daughters HPV Program

24 Nov 2015 | Teaching Materials | Contributor(s): Maria E. Fernandez

The Por Nuestras Hijas/For Our Daughters HPV program is an interactive, culturally appropriate HPV education program which includes a print fotonovela and a tailored interactive multimedia intervention (TIMI). The TIMI runs on iPads and also available on the web and mobile platforms. The program...

Screening for Small Molecules: Target Discovery Against miRNAs for Breast Cancer Treatment

18 Aug 2015 | Presentations | Contributor(s): Odemaris Narvaez del Pilar

Breast cancer is one of the leading causes of cancer related deaths and morbidity among women worldwide. Identifying new targets and developing new therapies is very important in order to improve patient outcomes and minimize this health burden. MicroRNAs, a type of non-coding RNA, are potential...

September 2021 CWIG Webinar Slides - Junjun Zhang

27 Dec 2021 | Presentations | Contributor(s): Alan Zheng

Standards Portal CDEs Complete View

15 Mar 2014 | Teaching Materials | Contributor(s): Denise Warzel, Ann Christine Catlin, Sumudinie fernando

This DataView on this resource page is used to explore the Standards Portal CDEsUse the DataView provided on this resource page to navigate, browse, search, explore and download the complete set of columns for NCI common data elements standards at the Hub. These CDEs are brought to the Hub for...

Standards Portal CRFs Common Data Fields

19 Mar 2014 | Downloads | Contributor(s): Denise Warzel, Sumudinie fernando, Ann Christine Catlin

This DataView is for the Common Data Fields of the Standards Portal CRFsUse this DataView to browse, search, explore and download the essential set of columns for NCI case report form standards at the Hub. These CRFs were brought to the Hub for clarification, discussion and discovery. They were...

Standards Portal CRFs Complete View

19 Mar 2014 | Downloads | Contributor(s): Denise Warzel, Sumudinie fernando, Ann Christine Catlin

This DataView resource page is for the Standards Portal CRFsUse this DataView to browse,search, explore and download the complete set of columns for NCI case report form standards at the Hub. These CRFs were brought to the Hub for clarification, discussion and discovery. They were assembled by...

Standards Portal Vocabulary DataView

15 Mar 2014 | Teaching Materials | Contributor(s): Sherri de Coronado, Denise Warzel, Ann Christine Catlin, Sumudinie fernando

The DataView for terminology referenced/used by the CDEs and CRFs currently contained in the Standards PortalThe DataView on this resource page can be used to browse, search, explore and download the NCI concepts for vocabulary referenced by the CDEs and CRFs uploaded to the Standards Portal....

TCGA Common Data Elements

15 Mar 2014 | Teaching Materials | Contributor(s): Ann Christine Catlin, Sumudinie fernando, Denise Warzel

TCGA Common Data ElementsTCGA version 2.6 CDEs are the standard elements that were used in validation of clinical data in the TCGA 2.6 data files. The data files are available for download at the Data Matrix. This resource page at the NCIP HUB presents the CDEs for easy search and discovery....

Text Messaging and Phone Calls as Tools to Promote Healthy Behaviors among Hispanic Populations

24 Nov 2015 | Teaching Materials | Contributor(s): Laura Leticia Nervi, Barbara Damron, Maria Otero, Andrew Sussman, Dolores Guest

Title: Text Messaging and Phone Calls as Tools to Promote Healthy Behaviors among Hispanic Populations   Objectives: The primary aim of this project was to evaluate the use of text messaging and phone calls to motivate Hispanic adult males and females to increase their daily physical...

Text Messaging as a Method to Increase Oral Chemotherapy Adherence in Hispanic Cancer Populations

23 Nov 2015 | Teaching Materials | Contributor(s): Laura Leticia Nervi, Barbara Damron, Andrew Sussman, Dolores Guest

Title: Text Messaging as a Method to Increase Oral Chemotherapy Adherence in Hispanic Cancer Populations:  Patient and Provider Feasibility Surveys Objectives: The purpose of this study was to explore the feasibility of conducting an interventional study to evaluate the effectiveness of text...