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  1. Human Disease Ontology

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    21 Sep 2016 | Contributor(s): Lynn Schriml

    The Disease Ontology has been developed as a standardized ontology for human disease, since 2003, with the purpose of providing the biomedical community with manual curated, consistent, reusable and sustainable descriptions of human disease terms, phenotype characteristics and related...

  2. Informatics to enable Routine Personalized Cancer Therapy (IPCT)

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    18 Feb 2014 | Contributor(s): Elmer V. Bernstam, Funda Meric-Bernstam

  3. Informatics to enable Routine Personalized Cancer Therapy (IPCT)

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    18 Feb 2014 | Contributor(s): Elmer V. Bernstam, Funda Meric-Bernstam

  4. Informatics Tools for High-throughput Analysis of Cancer Mutations

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    15 Jan 2014 | Contributor(s): Michael C Ryan, Rachel Karchin

  5. Informatics Tools for High-throughput Analysis of Cancer Mutations

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    15 Jan 2014 | Contributor(s): Michael C Ryan, Rachel Karchin

  6. Integrated analysis of breast cancer cell lines reveals unique signaling pathways

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    16 Sep 2014 | Contributor(s): Laura M Heiser, Nicholas J Wang, Carolyn L Talcott, Keith R Laderoute, Merrill Knapp, Yinghui Guan, Zhi Hu, Safiyyah Ziyad, Barbara L Weber, Sylvie Laquerre, Jeffrey R Jackson, Richard F Wooster, Wen Lin Kuo, Joe W Gray, Paul T Spellman

    AbstractBackgroundCancer is a heterogeneous disease resulting from the accumulation of genetic defects that negatively impact control of cell division, motility, adhesion and apoptosis. Deregulation in signaling along the EgfR-MAPK pathway is common in breast cancer, though the manner in which...

  7. Integrative Cancer Biology Program Datasets

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    26 Apr 2016 | Series | Contributor(s): Jonathan Bistline, Michael Reich

    The NCI-ICBP promotes an integrative/systems approach to the study of cancer biology. The Program encourages scientists to study cancer as a complex biological system. Information gained from these studies are used to build reliable and testable predictive computation models of cancer processes...

  8. Introduction to the Trinity Cancer Transcriptome Analysis Toolkit

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    05 Feb 2015 | Teaching Materials | Contributor(s): Brian Haas, Aviv Regev, Bill Barnett

    This short video provides an overview of our ITCR-funded effort to leverage RNA-Seq and de novo transcriptome assembly to assist researchers in studying cancer transcriptomes.  Visit our NCGAS Trinity/Galaxy portal to access these compute...

  9. Introduction to the Trinity Cancer Transcriptome Analysis Toolkit

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    05 Feb 2015 | Teaching Materials | Contributor(s): Brian Haas, Aviv Regev, Bill Barnett

    This short video provides an overview of our ITCR-funded effort to leverage RNA-Seq and de novo transcriptome assembly to assist researchers in studying cancer transcriptomes.  Visit our NCGAS Trinity/Galaxy portal to access these compute...

  10. ITCR Monthly Teleconference September 4, 2015

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    07 Oct 2015 | Presentations | Contributor(s): Juli Klemm

     

  11. ITCR PI Meeting June 2014 Presentations

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    23 Jun 2014 | Series

    Informatics Technology for Cancer Research (ITCR) Initiative held its Annual PI Meeting on June 12-13, 2014 in Rockville, MD. This series contains the presentations given at the meeting.

  12. LBL ICBP50 integrative genomic data

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    13 Nov 2014 | Downloads | Contributor(s): Joe Gray, Jonathan Bistline

    From Joe Gray, Lawrence Berkeley National Laboratory.  There are seventeen (17) files in this study: Affymetrix U133A gene expression data (icbp_u133a.gct) Affymetrix U133A gene expression data (ICBP_U133a.zip) Affymetrix splice junction exon-exon data (ICBP_Junction.zip) Affymetrix...

  13. Life after MOOCS: Online Science Education Needs a New Revolution

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    03 Feb 2017 | Presentations | Contributor(s): Phillip Compeau

    ITCR Monthly PI Meeting, February 3, 2017 Presentation by Phillip Compeau (Carnegie Mellon U.)

  14. Multiclass cancer diagnosis using tumor gene expression signatures

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    10 Nov 2014 | Downloads

    Experiment Description:    The optimal treatment of patients with cancer depends on establishing accurate diagnoses by using a complex combination of clinical and histopathological data. In some instances, this task is difficult or impossible because of atypical clinical...

  15. NANOANALYTICS OF EXTRACELLULAR VESICLES – Standards for isolation, characterization and reporting

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    26 May 2017 | Presentations | Contributor(s): Shivani Sharma

    Nano WG presentation on May 25, 2017. Presentation by Dr.  Shivani Sharma, Associate Director of the Nano Pico Characterization Lab, UCLA. Nanoscale characterization of exosomes and their use disease biomarkers and drug delivery agents

  16. Next-Generation Clustered Heat Maps (NG-­CHM)

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    07 Oct 2015 | Presentations | Contributor(s): Weinstein John, Bradley Broom

    Clustered Heat Maps (CHMs) have been referred to as the ubiquitous visual icons of post-genomic biology -- the most frequent type of visualization for large molecular profiling databases. However, “traditional” CHMs are static images -- a serious limitation. Accordingly, we have now...

  17. Notes from the ITCR Annual Meeting May 27-28, 2015

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    10 Jun 2015 | Downloads | Contributor(s): Ishwar Chandramouliswaran, Juli Klemm

    Notes from the ITCR Annual Meeting May 27-28, 2015

  18. Open source diffusion MRI technology for brain cancer research

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    07 Oct 2015 | Presentations | Contributor(s): Lauren O\'Donnell

    Using measurements of water diffusion, dMRI can give unique insights into the microstructure and cellular orientation of tissues. There is a growing awareness in the neurosurgery community that diffusion models must move beyond the current clinical standard of the diffusion tensor for better...

  19. Pathology Image Informatics Platform for visualization, analysis and management

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    07 Oct 2015 | Presentations | Contributor(s): Metin Gurcan, Anant Madabhushi, Anne Martel

    This multi-institutional proposal seeks to expand on an existing, freely available pathology image viewer (Sedeen Image Viewer) to create a pathology informatics platform (PIIP) for managing, annotating, sharing, and quantitatively analyzing digital Pathology Imaging (DPI) data. Sedeen has become...

  20. pRainBow optical barcoding library

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    14 Aug 2014 | Reagents | Contributor(s): Andries Zijlstra

    Note: this is a work in progress. About: pRainBow is a library of lentiviral vectors designed to allow for fluorescent labeling of cells with one of 7 distinct fluorescent proteins. Composition: How to obtain: How to cite: Other information:Good global...