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GenomeSpace Presentation
08 Feb 2016 | Presentations | Contributor(s): Michael Reich
GenomeSpace (http://www.genomespace.org) is a cloud-based, cooperative community resource that currently supports the streamlined interaction of 20 bioinformatics tools and data resources. To facilitate integrative analysis by non-programmers, it offers a growing set of 'recipes',...
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HUBzero: A platform for dissemination and collaboration in Computational Science and Engineering
07 Aug 2015 | Publications | Contributor(s): Michael McLennan, Rick Kennell
The HUBzero cyberinfrastructure lets scientific researchers work together online to develop tools. Other researchers can then access the resulting tools using an ordinary Web browser and launch simulation runs on the national Grid infrastructure, without having to download or...
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HUBzero: A Web-based Platform for research, Education and Scientific Collaboration
11 Sep 2013 | Presentations | Contributor(s): Michael McLennan
Imagine an app store for scientists, engineers, and educators filled with simulation and modeling tools — not simple Java applets, but real research codes that tackle difficult problems and may require substantial computing power drawn from the Cloud. Imagine a new way of publishing...
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Informatics to enable Routine Personalized Cancer Therapy (IPCT)
18 Feb 2014 | Presentations | Contributor(s): Elmer V. Bernstam, Funda Meric-Bernstam
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Informatics Tools for High-throughput Analysis of Cancer Mutations
15 Jan 2014 | Presentations | Contributor(s): Michael C Ryan, Rachel Karchin
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Integrated analysis of breast cancer cell lines reveals unique signaling pathways
16 Sep 2014 | Publications | Contributor(s): Laura M Heiser, Nicholas J Wang, Carolyn L Talcott, Keith R Laderoute, Merrill Knapp, Yinghui Guan, Zhi Hu, Safiyyah Ziyad, Barbara L Weber, Sylvie Laquerre, Jeffrey R Jackson, Richard F Wooster, Wen Lin Kuo, Joe W Gray, Paul T Spellman
AbstractBackgroundCancer is a heterogeneous disease resulting from the accumulation of genetic defects that negatively impact control of cell division, motility, adhesion and apoptosis. Deregulation in signaling along the EgfR-MAPK pathway is common in breast cancer, though the manner in which...
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Integrative Cancer Biology Program Datasets
26 Apr 2016 | Series | Contributor(s): Jonathan Bistline, Michael Reich
The NCI-ICBP promotes an integrative/systems approach to the study of cancer biology. The Program encourages scientists to study cancer as a complex biological system. Information gained from these studies are used to build reliable and testable predictive computation models of cancer processes...
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Introduction to the Trinity Cancer Transcriptome Analysis Toolkit
05 Feb 2015 | Teaching Materials | Contributor(s): Brian Haas, Aviv Regev, Bill Barnett
This short video provides an overview of our ITCR-funded effort to leverage RNA-Seq and de novo transcriptome assembly to assist researchers in studying cancer transcriptomes. Visit our NCGAS Trinity/Galaxy portal to access these compute...
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ITCR Monthly Teleconference September 4, 2015
07 Oct 2015 | Presentations | Contributor(s): Juli Klemm
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ITCR PI Meeting June 2014 Presentations
23 Jun 2014 | Series
Informatics Technology for Cancer Research (ITCR) Initiative held its Annual PI Meeting on June 12-13, 2014 in Rockville, MD. This series contains the presentations given at the meeting.
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Jaqpot - An open-source web platform for creating, using, testing and sharing predictive models in nano-informatics
20 Jun 2019 | Presentations | Contributor(s): Haralambos Sarimveis
Nano WG June 20, 2019Computational models that predict physicochemical properties, biokinetics or adverse biological effects of Engineered Nanomaterials (ENMs) are becoming increasingly important to support risk assessment and safety-by-design. This is primarily due to cost-saving and...
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LBL ICBP50 integrative genomic data
13 Nov 2014 | Downloads | Contributor(s): Joe Gray, Jonathan Bistline
From Joe Gray, Lawrence Berkeley National Laboratory. There are seventeen (17) files in this study: Affymetrix U133A gene expression data (icbp_u133a.gct) Affymetrix U133A gene expression data (ICBP_U133a.zip) Affymetrix splice junction exon-exon data (ICBP_Junction.zip) Affymetrix...
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Life after MOOCS: Online Science Education Needs a New Revolution
03 Feb 2017 | Presentations | Contributor(s): Phillip Compeau
ITCR Monthly PI Meeting, February 3, 2017 Presentation by Phillip Compeau (Carnegie Mellon U.)
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NanoInformatics Knowledge Commons Curation Team: Building the Data Dictionary to Enrich Data Curation
11 Jul 2018 | Presentations | Contributor(s): Jaleesia Amos, Yuan Tian, Mervi Heiskanen
Nano WG Presentation, May 31st, 2018 Organized storing of data using informed-decision making to determine what information should be curated, when data curation is complete, and how to identify high-quality data. Purpose of NIKC structure & curation process: tell the story of...
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Next-Generation Clustered Heat Maps (NG-CHM)
07 Oct 2015 | Presentations | Contributor(s): Weinstein John, Bradley Broom
Clustered Heat Maps (CHMs) have been referred to as the ubiquitous visual icons of post-genomic biology -- the most frequent type of visualization for large molecular profiling databases. However, “traditional” CHMs are static images -- a serious limitation. Accordingly, we have now...
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Notes from the ITCR Annual Meeting May 27-28, 2015
10 Jun 2015 | Downloads | Contributor(s): Ishwar Chandramouliswaran, Juli Klemm
Notes from the ITCR Annual Meeting May 27-28, 2015
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Open source diffusion MRI technology for brain cancer research
07 Oct 2015 | Presentations | Contributor(s): Lauren O\'Donnell
Using measurements of water diffusion, dMRI can give unique insights into the microstructure and cellular orientation of tissues. There is a growing awareness in the neurosurgery community that diffusion models must move beyond the current clinical standard of the diffusion tensor for better...
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Overview on HUBzero - Building Scientific Communities Online
03 Sep 2013 | Teaching Materials | Contributor(s): Michael McLennan
This is a white paper/publication on the HUB and how one can build online communities using the HUBzero platform. See the tab on supporting documents for a video presentation.
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Pathology Image Informatics Platform for visualization, analysis and management
07 Oct 2015 | Presentations | Contributor(s): Metin Gurcan, Anant Madabhushi, Anne Martel
This multi-institutional proposal seeks to expand on an existing, freely available pathology image viewer (Sedeen Image Viewer) to create a pathology informatics platform (PIIP) for managing, annotating, sharing, and quantitatively analyzing digital Pathology Imaging (DPI) data. Sedeen has become...
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Providing National Cyberinfrastructure to Biologists, esp. Genomicists
02 Sep 2016 | Presentations | Contributor(s): Tom Doek, Mervi Heiskanen
National Center for Genome Analysis Support (NCGAS) provides access to High Performance Computing resources for biologists. NCGAS also maintains a curated set of applications and Galaxy instances of their software, as well as provides bioinformatics expertise.