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Pathology Image Informatics Platform for visualization, analysis and management
07 Oct 2015 | Contributor(s): Metin Gurcan, Anant Madabhushi, Anne Martel
This multi-institutional proposal seeks to expand on an existing, freely available pathology image viewer (Sedeen Image Viewer) to create a pathology informatics platform (PIIP) for managing, annotating, sharing, and quantitatively analyzing digital Pathology Imaging (DPI) data. Sedeen has become...
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Next-Generation Clustered Heat Maps (NG-CHM)
07 Oct 2015 | Contributor(s): Weinstein John, Bradley Broom
Clustered Heat Maps (CHMs) have been referred to as the ubiquitous visual icons of post-genomic biology -- the most frequent type of visualization for large molecular profiling databases. However, “traditional” CHMs are static images -- a serious limitation. Accordingly, we have now...
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Open source diffusion MRI technology for brain cancer research
07 Oct 2015 | Contributor(s): Lauren O\'Donnell
Using measurements of water diffusion, dMRI can give unique insights into the microstructure and cellular orientation of tissues. There is a growing awareness in the neurosurgery community that diffusion models must move beyond the current clinical standard of the diffusion tensor for better...
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ITCR Monthly Teleconference September 4, 2015
07 Oct 2015 | Contributor(s): Juli Klemm
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Brain Cancer Imaging Analytics
02 Oct 2015 | Presentations | Contributor(s): Christos Davatzikos
The transition of oncologic imaging from its “industrial era” to it is “information era” demands analytical methods that 1) extract information from this data that is clinically and biologically relevant; 2) integrate imaging, clinical, and genomic data via rigorous...
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Screening for Small Molecules: Target Discovery Against miRNAs for Breast Cancer Treatment
18 Aug 2015 | Presentations | Contributor(s): Odemaris Narvaez del Pilar
Breast cancer is one of the leading causes of cancer related deaths and morbidity among women worldwide. Identifying new targets and developing new therapies is very important in order to improve patient outcomes and minimize this health burden. MicroRNAs, a type of non-coding RNA, are potential...
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Data Readiness Levels
13 Aug 2015 | Teaching Materials
Nanotechnology Signature InitiativeNanotechnology Knowledge Infrastructure (NKI):Enabling National Leadership in Sustainable DesignDraft Discussion Document: May 9, 2013
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HUBzero: A platform for dissemination and collaboration in Computational Science and Engineering
07 Aug 2015 | Publications | Contributor(s): Michael McLennan, Rick Kennell
The HUBzero cyberinfrastructure lets scientific researchers work together online to develop tools. Other researchers can then access the resulting tools using an ordinary Web browser and launch simulation runs on the national Grid infrastructure, without having to download or...
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Home Health Party: Colorectal Cancer Knowledge
16 Jul 2015 | Teaching Materials | Contributor(s): Kathy Briant
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Trinity: RNA-Seq De novo Assembly Application
30 Jun 2015 | External Applications | Contributor(s): Grabherr MG, Brian Haas, Yassour M, Levin JZ, Thompson DA, Amit I, Adiconis X, Fan L, Raychowdhury R, Zeng Q, Chen Z, Mauceli E, Hacohen N, Gnirke A, Rhind N, Di Palma F, Birren BW, Nusbaum C, Lindblad-toh K, Friedman N, Regev A
Quick Guide for the ImpatientTrinity assembles transcript sequences from Illumina RNA-Seq data.Download Trinity here.Build Trinity by typing make : ; in the base installation directory.Assemble RNA-Seq data like so:Trinity --seqType fq --left reads_1.fq --right reads_2.fq...
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CRAVAT - Cancer-Related Analysis of Variants Toolkit
23 Jun 2015 | External Applications | Contributor(s): Rachel Karchin, Michael C Ryan
cravat is a bioinformatics pipeline : ; that performs high-throughput cancer-related analysis of variants. it : ; utilizes three applications: CHASM (Cancer-Specific Analysis of Somatic Mutations), VEST and SVN-Get. More information on these tools is available at CHASM Software.Release...
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Tools for Creation of Integrated Data Repository for Cancer Research
16 Jun 2015 | Presentations | Contributor(s): Guoqian Jiang
Admin Supplement Proposal Parent Projects: DeepPhe (PIs: Savova and Jacobson) caCDE-QA (PI: Jiang)
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A Semantic Web-based Quality Assurance Tool for Cancer Study Common Data Elements
16 Jun 2015 | Presentations | Contributor(s): Guoqian Jiang
A poster presentation from the caCDE-QA project (PI: Jiang)
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Notes from the ITCR Annual Meeting May 27-28, 2015
10 Jun 2015 | Downloads | Contributor(s): Ishwar Chandramouliswaran, Juli Klemm
Notes from the ITCR Annual Meeting May 27-28, 2015
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The World of HUBzero
11 Feb 2015 | Presentations | Contributor(s): Michael McLennan
This part of a demo/presentation from the Force2015 conference giving you a 9 1/2 minute overview of the HUBzero platform and its capabilities - NCIP Hub is based on the HUBzero platform.[[Youtube(p_hpwoiXvEE,300,200)]]
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Introduction to the Trinity Cancer Transcriptome Analysis Toolkit
05 Feb 2015 | Teaching Materials | Contributor(s): Brian Haas, Aviv Regev, Bill Barnett
This short video provides an overview of our ITCR-funded effort to leverage RNA-Seq and de novo transcriptome assembly to assist researchers in studying cancer transcriptomes. Visit our NCGAS Trinity/Galaxy portal to access these compute...
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Some Thoughts on Reproducibility
05 Dec 2014 | Presentations | Contributor(s): John Rumble
Nano WG December 4, 2014
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Data, Metadata and "Data Quality" for Databases
05 Dec 2014 | Presentations | Contributor(s): Frederick C. Klaessig, Mervi Heiskanen
Nano WG December 4, 2014
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Data ReproducibilityNanotechnology Knowledge Infrastructure Data Curation
05 Dec 2014 | Presentations | Contributor(s): Martin Fritts
Nano WG presentation on December 4, 2014
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CRAVAT Introduction Video - Cancer Related Analysis of Variants
03 Dec 2014 | Teaching Materials | Contributor(s): Michael C Ryan
This video provides a brief overview of the CRAVAT web service(http://www.cravat.us/). CRAVAT provides annotation and analysis of cancer mutations. CRAVAT is free, very easy to use, and can handle large volumes of mutations.[[Youtube(xovmIy11Bcs)]]Please switch to 1080 resolution and watch...