Screening for Small Molecules: Target Discovery Against miRNAs for Breast Cancer Treatment

18 Aug 2015 | Contributor(s): Odemaris Narvaez del Pilar

Breast cancer is one of the leading causes of cancer related deaths and morbidity among women worldwide. Identifying new targets and developing new therapies is very important in order to improve patient outcomes and minimize this health burden. MicroRNAs, a type of non-coding RNA, are potential...

NCIP Hub QIN Workshop - March 3, 2015

19 Mar 2015 | Presentations | Contributor(s): Michael McLennan

Mike McLennan, director of HUBzero, presented an overview of basic NCIP Hub functionality to the QIN group on March 3, 2015. The presentation included an overview of the "hub" and HUBzero, and touched upon functionality such as projects, groups, resources and information sharing. The...

Introduction to the Trinity Cancer Transcriptome Analysis Toolkit

05 Feb 2015 | Teaching Materials | Contributor(s): Brian Haas, Aviv Regev, Bill Barnett

This short video provides an overview of our ITCR-funded effort to leverage RNA-Seq and de novo transcriptome assembly to assist researchers in studying cancer transcriptomes.  Visit our NCGAS Trinity/Galaxy portal to access these compute...

Databases on NCIP Hub

21 Nov 2014 | Teaching Materials | Contributor(s): Patrick Mulligan

Overview and demo of the database functionality on NCIP Hub. Further documentation on database functionality is included in the "Supporting Documentation" section.

Building Online Scientific Communities via NCIP Hub

17 Nov 2014 | Teaching Materials | Contributor(s): Ishwar Chandramouliswaran

Overview of how NCIP Hub can be used to build online scientific communities.

LBL ICBP50 integrative genomic data

13 Nov 2014 | Downloads | Contributor(s): Joe Gray, Jonathan Bistline

From Joe Gray, Lawrence Berkeley National Laboratory.  There are seventeen (17) files in this study: Affymetrix U133A gene expression data (icbp_u133a.gct) Affymetrix U133A gene expression data (ICBP_U133a.zip) Affymetrix splice junction exon-exon data (ICBP_Junction.zip) Affymetrix...

Baylor Residual breast cancer

13 Nov 2014 | Downloads | Contributor(s): Creighton C, Lewis M, Chang J, Jonathan Bistline

Residual breast cancers after conventional therapy display mesenchymal as tumor-initiating features.  There are four (4) files included in this study: Sample Annotation (combined_sample_annotation.txt) Gene expression data from CD44+/CD24- cells sorted by flow cytometry (GSE7513.gct) Human...

Multiclass cancer diagnosis using tumor gene expression signatures

10 Nov 2014 | Downloads

Experiment Description:    The optimal treatment of patients with cancer depends on establishing accurate diagnoses by using a complex combination of clinical and histopathological data. In some instances, this task is difficult or impossible because of atypical clinical...

Resources on NCIP Hub

22 Sep 2014 | Teaching Materials | Contributor(s): Lisa Mahoney

This is a presentation given as part of the NCIP Hub Webinar Series. It reviews at a high level what resources are, why and when to use them, and how to contribute.

Integrated analysis of breast cancer cell lines reveals unique signaling pathways

16 Sep 2014 | Publications | Contributor(s): Laura M Heiser, Nicholas J Wang, Carolyn L Talcott, Keith R Laderoute, Merrill Knapp, Yinghui Guan, Zhi Hu, Safiyyah Ziyad, Barbara L Weber, Sylvie Laquerre, Jeffrey R Jackson, Richard F Wooster, Wen Lin Kuo, Joe W Gray, Paul T Spellman

AbstractBackgroundCancer is a heterogeneous disease resulting from the accumulation of genetic defects that negatively impact control of cell division, motility, adhesion and apoptosis. Deregulation in signaling along the EgfR-MAPK pathway is common in breast cancer, though the manner in which...

Why Should You Care About Accessibility of Your Contributed Content?

02 Jun 2014 | Teaching Materials

Most people today can hardly conceive of life without the internet. Some have argued that no other single invention has been more revolutionary since Gutenberg's printing press in the 1400s. Now, at the click of a mouse, the world can be "at your fingertips"—that is, if you...

Collections on NCIP Hub

02 Jun 2014 | Teaching Materials | Contributor(s): Ishwar Chandramouliswaran, Lisa Mahoney

NCIP Hub Webinar Series presentation given on April 24, 2014. The presentation explains what collections are, and how and when to use them.

NCIP Hub Dashboard Tutorial

15 Apr 2014 | Teaching Materials | Contributor(s): Lisa Mahoney

This is a short "how-to" video to familiarize users with the customizable dashboard on NCIP Hub.