CEINT's NanoPHEAT Project : Integrating Exposure and Toxicity Data to Build Risk Forecasting Tools
16 Apr 2020 | Contributor(s): Mark Wiesner, Jaleesia Amos
The NanoPHEAT tool (Nano Product Hazard and Exposure Assessment Tool) is built to compile dose-response curves from literature, including hundreds of papers, and calculates the estimated exposure to nanoparticles as released from real products, based on some in-house experimental values that we...
NanoFASE models and exposure assessment: overview, lessons learned and future developments
09 Apr 2020 | Contributor(s): Stephen Lofts
Nano WG April 2, 2020: The H2020 NanoFASE project focused on the development of an environmental Exposure Assessment Framework for Nanomaterials. Key to the development of this framework were a number of environmental fate models: SimpleBox4Nano, a screening level multimedia model of...
The Materials Genome Initiative and the Materials Data Infrastructure
31 Mar 2020 | Contributor(s): James Warren
Presentation on current efforts to build out the materials data infrastructure in support of the US Materials Genome Initiative and discussion on incentives that need to be in place to realize program goals.
ISA-TAB-Nano 1.3 release review
09 Mar 2020 | Contributor(s): Mervi Heiskanen, Mervi Anneli Heiskanen
Nano WG January 30th, 2020Review of the new 1.3 release with the Nano WG
Advances in the reliability of nanotoxicity assays
27 Feb 2020 | Contributor(s): Elijah Petersen
Nano WG February 20, 2020Abstract: With the increasing usage of nanotechnology in consumer products, it is important to develop accurate methods to assess the potential adverse effects of engineered nanomaterials (ENMs) on humans or environmentally important organisms. However, many of these...
Nanomaterials & Scientific Committee on Consumer Safety: Overview with Focus on nano-hydroxyapatite and Silica
23 Jan 2020 | Contributor(s): Frederick C. Klaessig
Nano WG January 23, 2020The EU’s Scientific Committee on Consumer Safety advises the European Commission on the safety of products covered by the Cosmetics Directive, which includes personal care products as well as cosmetics. In the 2013-2016 time period, the Committee published...
Global Harmonization of Nanoinformatics: A Case Study in Convergence and Team Science
27 Nov 2019 | Contributor(s): Frederick C. Klaessig, Christine Ogilvie Hendren
Nano WG November 14, 2019National Nanotechnology Coordination Office (NNCO) sponsored Nanoinformatics presentation followed by discussion on Nanomaterial safety data integration with eNanoMapper database and eNanoMapper Ontology...
Read across in nanosafety research: Dissolution behaviour of a library of 37 nanomaterials in simplified physiological media
05 Nov 2019 | Contributor(s): Tassos Papadiamantis, Emily Guggenheim, Antreas Afantitis, Sophie Briffa, Georgia Melagraki, Iseult Lynch, Eugenia Valsami-Jones
NanoWorkingGroup, 31 October 2019The dissolution of engineered nanomaterials (ENMs) is a complex process, which remains poorly understood despite being one of the key prerequisites for the risk assessment of ENMs, and having a direct influence on toxicological and eco-toxicological effects....
Examples on Using Wikidata to Support Nanoinformatics Projects
13 Sep 2019 | Presentations | Contributor(s): Egon Willighagen
Nano WG Meeting September 12, 2019 Two years ago, a community survey resulted in a sketch of a linked data approach to nanosafety research . Interoperability of linked data enables the reuse, but linking databases is not trivial. Many resources are simply not FAIR enough for reuse yet,...
Some thoughts on our progress in defining and advancing nanoinformatics
01 Aug 2019 | Presentations | Contributor(s): Mark D Hoover
Nano WG Meeting November 1, 2018Discussion on Nano WG accomplishments and future directions.
Jaqpot - An open-source web platform for creating, using, testing and sharing predictive models in nano-informatics
20 Jun 2019 | Presentations | Contributor(s): Haralambos Sarimveis
Nano WG June 20, 2019Computational models that predict physicochemical properties, biokinetics or adverse biological effects of Engineered Nanomaterials (ENMs) are becoming increasingly important to support risk assessment and safety-by-design. This is primarily due to cost-saving and...
Transitioning to Predictive Analysis for Nanoparticle Biocorona Studies
14 May 2019 | Presentations | Contributor(s): Korin Wheeler
Nano WG April 18, 2019: Proteins adsorbed to nanomaterials in a biological environment mediate cellular recognition, uptake, and toxicity of nanomaterials. Here, Dr. Korin Wheeler presents the development of experimental methods to characterize this population of proteins (also...
Accelerating Nanotech Innovations Through a Safer-By-Design Approach, Safer Nanomaterials School
14 May 2019 | Presentations | Contributor(s): Philippe Sabatier
Nano WG May 9, 2019European Scientific Institute (ESI) Safer Nanomaterials School Introduction.
The history of chemical information and the materials of the future
25 Apr 2019 | Presentations | Contributor(s): Evan Hepler-Smith
Techniques, technologies, cultures, and infrastructures of information management played a central role in the development of the modern chemical sciences and the global chemicals industry since the late 19th century. Chemical databases and analytical techniques that privileged abstract,...
FAIR for NanoSafety: where do we stand?
05 Apr 2019 | Presentations | Contributor(s): Egon Willighagen
Nano WG April 4, 2019 Findable, Accessible, Interoperable, Reusable (FAIR) sharing of nanosafety data.
European Open Science Cloud: Concept and opportunities
26 Mar 2019 | Presentations | Contributor(s): Gergely Sipos
EOSC-hub is a 33 million Euro H2020 project that started in January 2018 with the involvement of over 100 institutes. In three years the project establishes the first elements of the European Open Science Cloud (EOSC) – the infrastructure aimed to accelerate and support the current...
Development of Targeted Nanomedicines via Machine Learning Processes
05 Mar 2019 | Presentations | Contributor(s): Daniel Heller
Nano WG February 21, 2019Description: We are using data science to facilitate the development of nanoparticle drugs incorporating kinase inhibitors with diverse chemical structures. Doing this work inspired us to bring together the nanoinformatics community...
Development of natural language processing tools for nanoparticle design
05 Mar 2019 | Presentations | Contributor(s): Nastassja Lewinski
Nano WG February 28, 2019: In this presentation, an introduction to the application of natural language processing techniques to nanotechnology data will be discussed. Natural language processing tools can aid in the automatic categorization, extraction, and analysis of data from...
Innovative Nanoinformatics models and tools: towards a Solid, verified and Integrated Approach to Predictive (eco)Toxicology (NanoSolveIT)
04 Feb 2019 | Presentations | Contributor(s): Antreas Afantitis
Nano WG January 17, 2019NanoSolveIT (a new H2020 nanoinformatics project) aspires to introduce a ground-breaking in silico Integrated Approach to Testing and Assessment (IATA) for the environmental health and safety of Nanomaterials (NM), implemented through a decision support system packaged...
nano-Ag: PBTK Models, Vblood & NIOSH
04 Feb 2019 | Presentations | Contributor(s): Frederick C. Klaessig, Mervi Heiskanen
Nano WG: January 31, 2019Nanoinformatics and computational models1.Examine a nano-Ag0 computational model used in a regulatory context2.SCCS has a nano-silver opinion3.NIOSH time period overlaps with the nanoinformatics roadmap4.NIOSH a case study for roadmap’s...