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Standards Portal CDEs Common Data Fields
19 Mar 2014 | Downloads | Contributor(s): Denise Warzel, Sumudinie fernando, Ann Christine Catlin
This DataView is for the Common Data Fields of the Standards Portal CDEsUse this DataView to browse, search, explore and download the essential set of columns for NCI common data elements standards at the Hub. These CDEs were brought to the Hub for clarification, discussion and discovery. They...
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Advanced Development of TIES - A Clinical Text Search Engine
18 Feb 2014 | Presentations | Contributor(s): Rebecca Crowley
Archived human tissues are an essential resource for translational research. Formalin-fixed, paraffin-embedded (FFPE) tissues from cancer patients are used in a wide range of assays, including RT-PCR, SNP profiling, multiplex biomarkers, imaging biomarkers, targeted exome, whole exome, and whole...
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Adverse Events Terminology Standards, Data Elements and Case Report Forms
15 Mar 2014 | Teaching Materials | Contributor(s): Sherri de Coronado, Ann Christine Catlin, Sumudinie fernando, Denise Warzel
Standards for coding, naming and grading adverse events (AEs) in cancer clinical trials include both cancer-focused and broader systems that all result from collaboration among academic, governmental, and pharmaceutical industry clinical investigators. They are all based on the need for...
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Baylor Residual breast cancer
13 Nov 2014 | Downloads | Contributor(s): Creighton C, Lewis M, Chang J, Jonathan Bistline
Residual breast cancers after conventional therapy display mesenchymal as tumor-initiating features. There are four (4) files included in this study: Sample Annotation (combined_sample_annotation.txt) Gene expression data from CD44+/CD24- cells sorted by flow cytometry (GSE7513.gct) Human...
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Breast Cancer Crossword
20 Nov 2015 | Teaching Materials | Contributor(s): Katelyn Schifano
This crossword is designed for use in social media as well as patient waiting areas.
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Community Health Worker Genetics Education Needs Assessment
23 Nov 2015 | Downloads | Contributor(s): Andria Reyes, Manuela Orjuela, Karen Schmitt, Andria Reyes, Grace Hillyer, Stephen Emerson
Our overarching goal is to develop and establish a cancer genetics curriculum that is pertinent, culturally sensitive and understandable by a community population who is not English dominant and of a lower literacy level than that of the general New York City population. The curriculum will teach...
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Getting Started at the Standards Portal Pilot
27 Mar 2014 | Teaching Materials | Contributor(s): Denise Warzel, Ann Christine Catlin
The Standards Portal Pilot is now available! (Click the link for the portal home page.)Why use the standards portal? See more information about its genesis and use cases in a study conducted for the VCDE caBIG community here. If you are participating in the Pilot, please join the...
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HUBzero: A platform for dissemination and collaboration in Computational Science and Engineering
07 Aug 2015 | Publications | Contributor(s): Michael McLennan, Rick Kennell
The HUBzero cyberinfrastructure lets scientific researchers work together online to develop tools. Other researchers can then access the resulting tools using an ordinary Web browser and launch simulation runs on the national Grid infrastructure, without having to download or...
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HUBzero: A Web-based Platform for research, Education and Scientific Collaboration
11 Sep 2013 | Presentations | Contributor(s): Michael McLennan
Imagine an app store for scientists, engineers, and educators filled with simulation and modeling tools — not simple Java applets, but real research codes that tackle difficult problems and may require substantial computing power drawn from the Cloud. Imagine a new way of publishing...
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Human Disease Ontology
21 Sep 2016 | External Applications | Contributor(s): Lynn Schriml
The Disease Ontology has been developed as a standardized ontology for human disease, since 2003, with the purpose of providing the biomedical community with manual curated, consistent, reusable and sustainable descriptions of human disease terms, phenotype characteristics and related...
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Informatics to enable Routine Personalized Cancer Therapy (IPCT)
18 Feb 2014 | Presentations | Contributor(s): Elmer V. Bernstam, Funda Meric-Bernstam
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Informatics Tools for High-throughput Analysis of Cancer Mutations
15 Jan 2014 | Presentations | Contributor(s): Michael C Ryan, Rachel Karchin
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Integrated analysis of breast cancer cell lines reveals unique signaling pathways
16 Sep 2014 | Publications | Contributor(s): Laura M Heiser, Nicholas J Wang, Carolyn L Talcott, Keith R Laderoute, Merrill Knapp, Yinghui Guan, Zhi Hu, Safiyyah Ziyad, Barbara L Weber, Sylvie Laquerre, Jeffrey R Jackson, Richard F Wooster, Wen Lin Kuo, Joe W Gray, Paul T Spellman
AbstractBackgroundCancer is a heterogeneous disease resulting from the accumulation of genetic defects that negatively impact control of cell division, motility, adhesion and apoptosis. Deregulation in signaling along the EgfR-MAPK pathway is common in breast cancer, though the manner in which...
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Integrative Cancer Biology Program Datasets
26 Apr 2016 | Series | Contributor(s): Jonathan Bistline, Michael Reich
The NCI-ICBP promotes an integrative/systems approach to the study of cancer biology. The Program encourages scientists to study cancer as a complex biological system. Information gained from these studies are used to build reliable and testable predictive computation models of cancer processes...
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Introduction to the Trinity Cancer Transcriptome Analysis Toolkit
05 Feb 2015 | Teaching Materials | Contributor(s): Brian Haas, Aviv Regev, Bill Barnett
This short video provides an overview of our ITCR-funded effort to leverage RNA-Seq and de novo transcriptome assembly to assist researchers in studying cancer transcriptomes. Visit our NCGAS Trinity/Galaxy portal to access these compute...
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LBL ICBP50 integrative genomic data
13 Nov 2014 | Downloads | Contributor(s): Joe Gray, Jonathan Bistline
From Joe Gray, Lawrence Berkeley National Laboratory. There are seventeen (17) files in this study: Affymetrix U133A gene expression data (icbp_u133a.gct) Affymetrix U133A gene expression data (ICBP_U133a.zip) Affymetrix splice junction exon-exon data (ICBP_Junction.zip) Affymetrix...
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Multiclass cancer diagnosis using tumor gene expression signatures
10 Nov 2014 | Downloads
Experiment Description: The optimal treatment of patients with cancer depends on establishing accurate diagnoses by using a complex combination of clinical and histopathological data. In some instances, this task is difficult or impossible because of atypical clinical...
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NANOANALYTICS OF EXTRACELLULAR VESICLES – Standards for isolation, characterization and reporting
26 May 2017 | Presentations | Contributor(s): Shivani Sharma
Nano WG presentation on May 25, 2017. Presentation by Dr. Shivani Sharma, Associate Director of the Nano Pico Characterization Lab, UCLA. Nanoscale characterization of exosomes and their use disease biomarkers and drug delivery agents
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NCI Standard CRFs
15 Mar 2014 | Teaching Materials | Contributor(s): Denise Warzel, Ann Christine Catlin, Sumudinie fernando
Working in conjunction with NCI has developed a collection of Standard Case Report Forms (CRFs) for use in developing new protocols. The project and its status are described here. The reuse of sections from standard CRFs helps to ensure that data collected in different studies is compatible and...
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Overview on HUBzero - Building Scientific Communities Online
03 Sep 2013 | Teaching Materials | Contributor(s): Michael McLennan
This is a white paper/publication on the HUB and how one can build online communities using the HUBzero platform. See the tab on supporting documents for a video presentation.