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  1. Standards Portal CRFs Common Data Fields

    19 Mar 2014 | Downloads | Contributor(s): Denise Warzel, Sumudinie fernando, Ann Christine Catlin

    This DataView is for the Common Data Fields of the Standards Portal CRFsUse this DataView to browse, search, explore and download the essential set of columns for NCI case report form standards at the Hub. These CRFs were brought to the Hub for clarification, discussion and discovery. They were...

  2. Why Use the Standards Portal at the Hub?

    19 Mar 2014 | Teaching Materials | Contributor(s): Denise Warzel, Sumudinie fernando, Ann Christine Catlin

    The materials attached to this page were provided by Baris Suzek, who at the time was the Informatics Project Lead at the Innovation Center for Biomedical Informatics at Georgetown University School of Medicine. He conducted a study for the caBIG VCDE community to help clarify some of the...

  3. Standards Portal Vocabulary DataView

    15 Mar 2014 | Teaching Materials | Contributor(s): Sherri de Coronado, Denise Warzel, Ann Christine Catlin, Sumudinie fernando

    The DataView for terminology referenced/used by the CDEs and CRFs currently contained in the Standards PortalThe DataView on this resource page can be used to browse, search, explore and download the NCI concepts for vocabulary referenced by the CDEs and CRFs uploaded to the Standards Portal....

  4. Standards Portal CDEs Complete View

    15 Mar 2014 | Teaching Materials | Contributor(s): Denise Warzel, Ann Christine Catlin, Sumudinie fernando

    This DataView on this resource page is used to explore the Standards Portal CDEsUse the DataView provided on this resource page to navigate, browse, search, explore and download the complete set of columns for NCI common data elements standards at the Hub. These CDEs are brought to the Hub for...

  5. NCI Standard CRFs

    15 Mar 2014 | Teaching Materials | Contributor(s): Denise Warzel, Ann Christine Catlin, Sumudinie fernando

    Working in conjunction with NCI has developed a collection of Standard Case Report Forms (CRFs) for use in developing new protocols. The project and its status are described here. The reuse of sections from standard CRFs helps to ensure that data collected in different studies is compatible and...

  6. Performance Status Scoring : a standards portal resource

    15 Mar 2014 | Teaching Materials | Contributor(s): Ann Christine Catlin, Sumudinie fernando, Denise Warzel, Angela Kummerow

    The scoring scale used may depend on patient population, disease, study goals and other criteria. Many definitions of the scale scoring do not match the standard.What is Performance Status?Performance status attempts to quantify the general well-being of cancer and other patients. The score...

  7. Adverse Events Terminology Standards, Data Elements and Case Report Forms

    15 Mar 2014 | Teaching Materials | Contributor(s): Sherri de Coronado, Ann Christine Catlin, Sumudinie fernando, Denise Warzel

    Standards for coding, naming and grading adverse events (AEs) in cancer clinical trials include both cancer-focused and broader systems that all result from collaboration among academic, governmental, and pharmaceutical industry clinical investigators. They are all based on the need for...

  8. TCGA Common Data Elements

    15 Mar 2014 | Teaching Materials | Contributor(s): Ann Christine Catlin, Sumudinie fernando, Denise Warzel

    TCGA Common Data ElementsTCGA version 2.6 CDEs are the standard elements that were used in validation of clinical data in the TCGA 2.6 data files. The data files are available for download at the Data Matrix. This resource page at the NCIP HUB presents the CDEs for easy search and discovery....

  9. U24 KickOff Steering Committee Meeting 022614

    12 Mar 2014 | Downloads | Contributor(s): Rebecca Crowley

    Kick of For Steering Committee - explains grant and discusses process for developing the TIES Cancer Research Network

  10. UCSC Xena System

    07 Mar 2014 | Presentations | Contributor(s): Jingchun Zhu

  11. Transcriptome assembly for genetic and functional analysis of cancer

    07 Mar 2014 | Presentations | Contributor(s): Aviv Regev, Brian Haas

  12. NCI / FNL Workshop on RAS Synthetic Lethality

    25 Feb 2014 | Downloads | Contributor(s): James Hartley

    "Synthetic lethality" is a term of classical genetics that refers to a combination of defective genes that is deadly together (synthetically, i.e., when both genes A and B are inactivated) but not when one or the other (A or B) is inactive. It is known that animal models of cancer can be...

  13. An Introduction to the RAS Project

    24 Feb 2014 | Downloads | Contributor(s): Frank McCormick, James Hartley

    Learn about the NCI RAS program.

  14. Informatics to enable Routine Personalized Cancer Therapy (IPCT)

    18 Feb 2014 | Presentations | Contributor(s): Elmer V. Bernstam, Funda Meric-Bernstam

  15. Advanced Development of TIES - A Clinical Text Search Engine

    18 Feb 2014 | Presentations | Contributor(s): Rebecca Crowley

    Archived human tissues are an essential resource for translational research. Formalin-fixed, paraffin-embedded (FFPE) tissues from cancer patients are used in a wide range of assays, including RT-PCR, SNP profiling, multiplex biomarkers, imaging biomarkers, targeted exome, whole exome, and whole...

  16. Genome-wide transcriptional sequencing identifies novel mutations in metabolic genes in human hepatocellular carcinoma (HCC)

    02 Feb 2014 | Publications

    Hepatocellular carcinoma (HCC) is the fifth most common cancer and the third most common cause of cancer mortality in the world. Although the association of HCC with chronic liver disease is well established, the exact etiology of HCC remains undefined. Here, we report the results of...

  17. Comparative proteomics of MCF-10A and MDA-MB-231 cells

    22 Jan 2014 | Downloads | Contributor(s): PS-OC Network, Parag Mallick

  18. The Cistrome Data Collection

    22 Jan 2014 | Presentations

  19. Informatics Tools for High-throughput Analysis of Cancer Mutations

    15 Jan 2014 | Presentations | Contributor(s): Michael C Ryan, Rachel Karchin

  20. Overview: The HUBzero Platform for Scientific Collaboration

    18 Dec 2013 | Presentations | Contributor(s): Michael McLennan

    This web site was created using a collaborative infrastructure called HUBzero, developed by Purdue University. HUBzero is the basis of nanoHUB.org and more than 50 other sites covering a wide range of scientific disciplines, including bio-fuels, microelectromechanical systems, cancer research,...