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  1. Integrated analysis of breast cancer cell lines reveals unique signaling pathways

    16 Sep 2014 | Contributor(s): Laura M Heiser, Nicholas J Wang, Carolyn L Talcott, Keith R Laderoute, Merrill Knapp, Yinghui Guan, Zhi Hu, Safiyyah Ziyad, Barbara L Weber, Sylvie Laquerre, Jeffrey R Jackson, Richard F Wooster, Wen Lin Kuo, Joe W Gray, Paul T Spellman

    AbstractBackgroundCancer is a heterogeneous disease resulting from the accumulation of genetic defects that negatively impact control of cell division, motility, adhesion and apoptosis. Deregulation in signaling along the EgfR-MAPK pathway is common in breast cancer, though the manner in which...

  2. ITCR PI Meeting June 2014 Presentations

    23 Jun 2014 | Series

    Informatics Technology for Cancer Research (ITCR) Initiative held its Annual PI Meeting on June 12-13, 2014 in Rockville, MD. This series contains the presentations given at the meeting.

  3. Cloud Supercomputer Aided Diagnostic Imaging Decision Support System

    18 Jun 2014 | Presentations | Contributor(s): Hiro Yoshida

    ITCR PI meeting presentation on project status.

  4. Quantitative Image Informatics for Cancer Research (QIICR)

    04 Apr 2014 | Presentations | Contributor(s): Andrey Fedorov, Ron Kikinis

  5. Informatics to enable Routine Personalized Cancer Therapy (IPCT)

    18 Feb 2014 | Presentations | Contributor(s): Elmer V. Bernstam, Funda Meric-Bernstam

  6. Advanced Development of TIES - A Clinical Text Search Engine

    18 Feb 2014 | Presentations | Contributor(s): Rebecca Crowley

    Archived human tissues are an essential resource for translational research. Formalin-fixed, paraffin-embedded (FFPE) tissues from cancer patients are used in a wide range of assays, including RT-PCR, SNP profiling, multiplex biomarkers, imaging biomarkers, targeted exome, whole exome, and whole...

  7. The Cistrome Data Collection

    22 Jan 2014 | Presentations

  8. Informatics Tools for High-throughput Analysis of Cancer Mutations

    15 Jan 2014 | Presentations | Contributor(s): Michael C Ryan, Rachel Karchin

  9. QIN HUBzero update

    28 Oct 2013 | Teaching Materials | Contributor(s): Jayashree Kalpathy-Cramer

    presentation for the QIN EC meeting 10/21/2013

  10. HUBzero: A Web-based Platform for research, Education and Scientific Collaboration

    11 Sep 2013 | Presentations | Contributor(s): Michael McLennan

    Imagine an app store for scientists, engineers, and educators filled with simulation and modeling tools — not simple Java applets, but real research codes that tackle difficult problems and may require substantial computing power drawn from the Cloud. Imagine a new way of publishing...

  11. Overview on HUBzero - Building Scientific Communities Online

    03 Sep 2013 | Teaching Materials | Contributor(s): Michael McLennan

    This is a white paper/publication on the HUB and how one can build online communities using the HUBzero platform. See the tab on supporting documents for a video presentation.