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  1. Workshop Tweets

    15 Aug 2017 | Publications | Contributor(s): Stephanie Morris

    Collated tweets from workshop and networking reception.

  2. NANOANALYTICS OF EXTRACELLULAR VESICLES – Standards for isolation, characterization and reporting

    26 May 2017 | Presentations | Contributor(s): Shivani Sharma

    Nano WG presentation on May 25, 2017. Presentation by Dr.  Shivani Sharma, Associate Director of the Nano Pico Characterization Lab, UCLA. Nanoscale characterization of exosomes and their use disease biomarkers and drug delivery agents

  3. Human Disease Ontology

    21 Sep 2016 | External Applications | Contributor(s): Lynn Schriml

    The Disease Ontology has been developed as a standardized ontology for human disease, since 2003, with the purpose of providing the biomedical community with manual curated, consistent, reusable and sustainable descriptions of human disease terms, phenotype characteristics and related...

  4. Integrative Cancer Biology Program Datasets

    26 Apr 2016 | Series | Contributor(s): Jonathan Bistline, Michael Reich

    The NCI-ICBP promotes an integrative/systems approach to the study of cancer biology. The Program encourages scientists to study cancer as a complex biological system. Information gained from these studies are used to build reliable and testable predictive computation models of cancer processes...

  5. Summary of the 2015 Epigenetic Engineering for Cancer Workshops

    22 Dec 2015 | Publications | Contributor(s): Tony Dickherber

    This document provides a general summary of the 2 virtual workshops held in Fall of 2015 to explore the suitability of epigenetic engineering tools to specifically modify epigenetic loci to study and/or treat cancer.

  6. Community Health Worker Genetics Education Needs Assessment

    23 Nov 2015 | Downloads | Contributor(s): Andria Reyes, Manuela Orjuela, Karen Schmitt, Andria Reyes, Grace Hillyer, Stephen Emerson

    Our overarching goal is to develop and establish a cancer genetics curriculum that is pertinent, culturally sensitive and understandable by a community population who is not English dominant and of a lower literacy level than that of the general New York City population. The curriculum will teach...

  7. Breast Cancer Crossword

    20 Nov 2015 | Teaching Materials | Contributor(s): Katelyn Schifano

    This crossword is designed for use in social media as well as patient waiting areas.

  8. Screening for Small Molecules: Target Discovery Against miRNAs for Breast Cancer Treatment

    18 Aug 2015 | Presentations | Contributor(s): Odemaris Narvaez del Pilar

    Breast cancer is one of the leading causes of cancer related deaths and morbidity among women worldwide. Identifying new targets and developing new therapies is very important in order to improve patient outcomes and minimize this health burden. MicroRNAs, a type of non-coding RNA, are potential...

  9. UCSC Biomedical Evidence Graph Demonstration

    03 Jun 2015 | Presentations | Contributor(s): Josh Stuart, ellrott

    The BMEG demonstration includes the following elements: 1) Organization of crowd-source challenges to develop best-of-breed methods including an overview of current DREAM projects, living benchmarks; 2) Enabling cloud-ready methods for mass compute with examples of recently...

  10. Seven Bridges Cancer Genomics Cloud Pilot TCGA 2015 symposium workshop presentation

    23 May 2015 | Presentations | Contributor(s): Deniz Kural

    Basic and translational cancer research creates the need to disseminate, manage, and interpret large heterogeneous datasets. The volume and complexity of the data now routinely generated by high-throughput technologies has become too costly for individual laboratories and many research...

  11. Introduction to the Trinity Cancer Transcriptome Analysis Toolkit

    05 Feb 2015 | Teaching Materials | Contributor(s): Brian Haas, Aviv Regev, Bill Barnett

    This short video provides an overview of our ITCR-funded effort to leverage RNA-Seq and de novo transcriptome assembly to assist researchers in studying cancer transcriptomes.  Visit our NCGAS Trinity/Galaxy portal to access these compute...

  12. Video: Learn how TIES can help manage research resources

    16 Jan 2015 | Presentations | Contributor(s): Girish Chavan, Rebecca Crowley

    https://www.youtube.com/watch?v=EzjAo9LJ4tg  

  13. CRAVAT Introduction Video - Cancer Related Analysis of Variants

    03 Dec 2014 | Teaching Materials | Contributor(s): Michael C Ryan

    This video provides a brief overview of the CRAVAT web service(http://www.cravat.us/).  CRAVAT provides annotation and analysis of cancer mutations. CRAVAT is free, very easy to use, and can handle large volumes of mutations.[[Youtube(xovmIy11Bcs)]]Please switch to 1080 resolution and watch...

  14. LBL ICBP50 integrative genomic data

    13 Nov 2014 | Downloads | Contributor(s): Joe Gray, Jonathan Bistline

    From Joe Gray, Lawrence Berkeley National Laboratory.  There are seventeen (17) files in this study: Affymetrix U133A gene expression data (icbp_u133a.gct) Affymetrix U133A gene expression data (ICBP_U133a.zip) Affymetrix splice junction exon-exon data (ICBP_Junction.zip) Affymetrix...

  15. Baylor Residual breast cancer

    13 Nov 2014 | Downloads | Contributor(s): Creighton C, Lewis M, Chang J, Jonathan Bistline

    Residual breast cancers after conventional therapy display mesenchymal as tumor-initiating features.  There are four (4) files included in this study: Sample Annotation (combined_sample_annotation.txt) Gene expression data from CD44+/CD24- cells sorted by flow cytometry (GSE7513.gct) Human...

  16. Multiclass cancer diagnosis using tumor gene expression signatures

    10 Nov 2014 | Downloads

    Experiment Description:    The optimal treatment of patients with cancer depends on establishing accurate diagnoses by using a complex combination of clinical and histopathological data. In some instances, this task is difficult or impossible because of atypical clinical...

  17. Integrated analysis of breast cancer cell lines reveals unique signaling pathways

    16 Sep 2014 | Publications | Contributor(s): Laura M Heiser, Nicholas J Wang, Carolyn L Talcott, Keith R Laderoute, Merrill Knapp, Yinghui Guan, Zhi Hu, Safiyyah Ziyad, Barbara L Weber, Sylvie Laquerre, Jeffrey R Jackson, Richard F Wooster, Wen Lin Kuo, Joe W Gray, Paul T Spellman

    AbstractBackgroundCancer is a heterogeneous disease resulting from the accumulation of genetic defects that negatively impact control of cell division, motility, adhesion and apoptosis. Deregulation in signaling along the EgfR-MAPK pathway is common in breast cancer, though the manner in which...

  18. Informatics to enable Routine Personalized Cancer Therapy (IPCT)

    18 Feb 2014 | Presentations | Contributor(s): Elmer V. Bernstam, Funda Meric-Bernstam

  19. Advanced Development of TIES - A Clinical Text Search Engine

    18 Feb 2014 | Presentations | Contributor(s): Rebecca Crowley

    Archived human tissues are an essential resource for translational research. Formalin-fixed, paraffin-embedded (FFPE) tissues from cancer patients are used in a wide range of assays, including RT-PCR, SNP profiling, multiplex biomarkers, imaging biomarkers, targeted exome, whole exome, and whole...

  20. Informatics Tools for High-throughput Analysis of Cancer Mutations

    15 Jan 2014 | Presentations | Contributor(s): Michael C Ryan, Rachel Karchin