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Multiclass cancer diagnosis using tumor gene expression signatures
10 Nov 2014
Experiment Description: The optimal treatment of patients with cancer depends on establishing accurate diagnoses by using a complex combination of clinical and histopathological data. In some instances, this task is difficult or impossible because of atypical clinical...
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Integrated analysis of breast cancer cell lines reveals unique signaling pathways
16 Sep 2014 | Contributor(s): Laura M Heiser, Nicholas J Wang, Carolyn L Talcott, Keith R Laderoute, Merrill Knapp, Yinghui Guan, Zhi Hu, Safiyyah Ziyad, Barbara L Weber, Sylvie Laquerre, Jeffrey R Jackson, Richard F Wooster, Wen Lin Kuo, Joe W Gray, Paul T Spellman
AbstractBackgroundCancer is a heterogeneous disease resulting from the accumulation of genetic defects that negatively impact control of cell division, motility, adhesion and apoptosis. Deregulation in signaling along the EgfR-MAPK pathway is common in breast cancer, though the manner in which...
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Informatics to enable Routine Personalized Cancer Therapy (IPCT)
18 Feb 2014 | Contributor(s): Elmer V. Bernstam, Funda Meric-Bernstam
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Advanced Development of TIES - A Clinical Text Search Engine
18 Feb 2014 | Contributor(s): Rebecca Crowley
Archived human tissues are an essential resource for translational research. Formalin-fixed, paraffin-embedded (FFPE) tissues from cancer patients are used in a wide range of assays, including RT-PCR, SNP profiling, multiplex biomarkers, imaging biomarkers, targeted exome, whole exome, and whole...
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Informatics Tools for High-throughput Analysis of Cancer Mutations
15 Jan 2014 | Contributor(s): Michael C Ryan, Rachel Karchin
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Overview: The HUBzero Platform for Scientific Collaboration
18 Dec 2013 | Presentations | Contributor(s): Michael McLennan
This web site was created using a collaborative infrastructure called HUBzero, developed by Purdue University. HUBzero is the basis of nanoHUB.org and more than 50 other sites covering a wide range of scientific disciplines, including bio-fuels, microelectromechanical systems, cancer research,...
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Overview on HUBzero - Building Scientific Communities Online
03 Sep 2013 | Teaching Materials | Contributor(s): Michael McLennan
This is a white paper/publication on the HUB and how one can build online communities using the HUBzero platform. See the tab on supporting documents for a video presentation.