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  1. Baylor Residual breast cancer

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    13 Nov 2014 | Downloads | Contributor(s): Creighton C, Lewis M, Chang J, Jonathan Bistline

    Residual breast cancers after conventional therapy display mesenchymal as tumor-initiating features.  There are four (4) files included in this study: Sample Annotation (combined_sample_annotation.txt) Gene expression data from CD44+/CD24- cells sorted by flow cytometry (GSE7513.gct) Human...

  2. Multiclass cancer diagnosis using tumor gene expression signatures

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    10 Nov 2014 | Downloads

    Experiment Description:    The optimal treatment of patients with cancer depends on establishing accurate diagnoses by using a complex combination of clinical and histopathological data. In some instances, this task is difficult or impossible because of atypical clinical...

  3. Integrated analysis of breast cancer cell lines reveals unique signaling pathways

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    16 Sep 2014 | Publications | Contributor(s): Laura M Heiser, Nicholas J Wang, Carolyn L Talcott, Keith R Laderoute, Merrill Knapp, Yinghui Guan, Zhi Hu, Safiyyah Ziyad, Barbara L Weber, Sylvie Laquerre, Jeffrey R Jackson, Richard F Wooster, Wen Lin Kuo, Joe W Gray, Paul T Spellman

    AbstractBackgroundCancer is a heterogeneous disease resulting from the accumulation of genetic defects that negatively impact control of cell division, motility, adhesion and apoptosis. Deregulation in signaling along the EgfR-MAPK pathway is common in breast cancer, though the manner in which...

  4. Informatics to enable Routine Personalized Cancer Therapy (IPCT)

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    18 Feb 2014 | Presentations | Contributor(s): Elmer V. Bernstam, Funda Meric-Bernstam

  5. Advanced Development of TIES - A Clinical Text Search Engine

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    18 Feb 2014 | Presentations | Contributor(s): Rebecca Crowley

    Archived human tissues are an essential resource for translational research. Formalin-fixed, paraffin-embedded (FFPE) tissues from cancer patients are used in a wide range of assays, including RT-PCR, SNP profiling, multiplex biomarkers, imaging biomarkers, targeted exome, whole exome, and whole...

  6. Informatics Tools for High-throughput Analysis of Cancer Mutations

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    15 Jan 2014 | Presentations | Contributor(s): Michael C Ryan, Rachel Karchin

  7. caNanoLab: data sharing to expedite the use of nanotechnology in biomedicine

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    13 Dec 2013 | Publications | Contributor(s): Sharon Gaheen, George W Hinkal, Stephanie A Morris, Michal Lijowski, Mervi Heiskanen, Juli Klemm

    The use of nanotechnology in biomedicine involves the engineering of nanomaterials to act as therapeutic carriers, targeting agents and diagnostic imaging devices. The application of nanotechnology in cancer aims to transform early detection, targeted therapeutics and cancer prevention and...

  8. QIN HUBzero update

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    28 Oct 2013 | Teaching Materials | Contributor(s): Jayashree Kalpathy-Cramer

    presentation for the QIN EC meeting 10/21/2013

  9. HUBzero: A Web-based Platform for research, Education and Scientific Collaboration

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    11 Sep 2013 | Presentations | Contributor(s): Michael McLennan

    Imagine an app store for scientists, engineers, and educators filled with simulation and modeling tools — not simple Java applets, but real research codes that tackle difficult problems and may require substantial computing power drawn from the Cloud. Imagine a new way of publishing...

  10. Overview on HUBzero - Building Scientific Communities Online

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    03 Sep 2013 | Teaching Materials | Contributor(s): Michael McLennan

    This is a white paper/publication on the HUB and how one can build online communities using the HUBzero platform. See the tab on supporting documents for a video presentation.