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  1. Trinity: RNA-Seq De novo Assembly Application

    30 Jun 2015 | External Applications | Contributor(s): Grabherr MG, Brian Haas, Yassour M, Levin JZ, Thompson DA, Amit I, Adiconis X, Fan L, Raychowdhury R, Zeng Q, Chen Z, Mauceli E, Hacohen N, Gnirke A, Rhind N, Di Palma F, Birren BW, Nusbaum C, Lindblad-toh K, Friedman N, Regev A

     Quick Guide for the ImpatientTrinity assembles transcript sequences from Illumina RNA-Seq data.Download Trinity here.Build Trinity by typing make : ; in the base installation directory.Assemble RNA-Seq data like so:Trinity --seqType fq --left reads_1.fq --right reads_2.fq...

  2. CRAVAT - Cancer-Related Analysis of Variants Toolkit

    23 Jun 2015 | External Applications | Contributor(s): Rachel Karchin, Michael C Ryan

    cravat is a bioinformatics pipeline : ; that performs high-throughput cancer-related analysis of variants. it : ; utilizes three applications: CHASM (Cancer-Specific Analysis of Somatic Mutations), VEST and SVN-Get. More information on these tools is available at CHASM Software.Release...

  3. Tools for Creation of Integrated Data Repository for Cancer Research

    16 Jun 2015 | Presentations | Contributor(s): Guoqian Jiang

    Admin Supplement Proposal Parent Projects: DeepPhe (PIs: Savova and Jacobson) caCDE-QA (PI: Jiang)

  4. A Semantic Web-based Quality Assurance Tool for Cancer Study Common Data Elements

    16 Jun 2015 | Presentations | Contributor(s): Guoqian Jiang

    A poster presentation from the caCDE-QA project (PI: Jiang)  

  5. Notes from the ITCR Annual Meeting May 27-28, 2015

    10 Jun 2015 | Downloads | Contributor(s): Ishwar Chandramouliswaran, Juli Klemm

    Notes from the ITCR Annual Meeting May 27-28, 2015

  6. UCSC Biomedical Evidence Graph Demonstration

    03 Jun 2015 | Presentations | Contributor(s): Josh Stuart, ellrott

    The BMEG demonstration includes the following elements: 1) Organization of crowd-source challenges to develop best-of-breed methods including an overview of current DREAM projects, living benchmarks; 2) Enabling cloud-ready methods for mass compute with examples of recently...

  7. Seven Bridges Cancer Genomics Cloud Pilot TCGA 2015 symposium workshop presentation

    23 May 2015 | Presentations | Contributor(s): Deniz Kural

    Basic and translational cancer research creates the need to disseminate, manage, and interpret large heterogeneous datasets. The volume and complexity of the data now routinely generated by high-throughput technologies has become too costly for individual laboratories and many research...

  8. Introduction to the Trinity Cancer Transcriptome Analysis Toolkit

    05 Feb 2015 | Teaching Materials | Contributor(s): Brian Haas, Aviv Regev, Bill Barnett

    This short video provides an overview of our ITCR-funded effort to leverage RNA-Seq and de novo transcriptome assembly to assist researchers in studying cancer transcriptomes.  Visit our NCGAS Trinity/Galaxy portal to access these compute...

  9. Introduction to the Trinity Cancer Transcriptome Analysis Toolkit

    05 Feb 2015 | Teaching Materials | Contributor(s): Brian Haas, Aviv Regev, Bill Barnett

    This short video provides an overview of our ITCR-funded effort to leverage RNA-Seq and de novo transcriptome assembly to assist researchers in studying cancer transcriptomes.  Visit our NCGAS Trinity/Galaxy portal to access these compute...

  10. Video: Learn how TIES can help manage research resources

    16 Jan 2015 | Presentations | Contributor(s): Girish Chavan, Rebecca Crowley

    https://www.youtube.com/watch?v=EzjAo9LJ4tg  

  11. CRAVAT Introduction Video - Cancer Related Analysis of Variants

    03 Dec 2014 | Teaching Materials | Contributor(s): Michael C Ryan

    This video provides a brief overview of the CRAVAT web service(http://www.cravat.us/).  CRAVAT provides annotation and analysis of cancer mutations. CRAVAT is free, very easy to use, and can handle large volumes of mutations.[[Youtube(xovmIy11Bcs)]]Please switch to 1080 resolution and watch...

  12. CRAVAT Introduction Video - Cancer Related Analysis of Variants

    03 Dec 2014 | Teaching Materials | Contributor(s): Michael C Ryan

    This video provides a brief overview of the CRAVAT web service(http://www.cravat.us/).  CRAVAT provides annotation and analysis of cancer mutations. CRAVAT is free, very easy to use, and can handle large volumes of mutations.[[Youtube(xovmIy11Bcs)]]Please switch to 1080 resolution and watch...

  13. LBL ICBP50 integrative genomic data

    13 Nov 2014 | Downloads | Contributor(s): Joe Gray, Jonathan Bistline

    From Joe Gray, Lawrence Berkeley National Laboratory.  There are seventeen (17) files in this study: Affymetrix U133A gene expression data (icbp_u133a.gct) Affymetrix U133A gene expression data (ICBP_U133a.zip) Affymetrix splice junction exon-exon data (ICBP_Junction.zip) Affymetrix...

  14. Baylor Residual breast cancer

    13 Nov 2014 | Downloads | Contributor(s): Creighton C, Lewis M, Chang J, Jonathan Bistline

    Residual breast cancers after conventional therapy display mesenchymal as tumor-initiating features.  There are four (4) files included in this study: Sample Annotation (combined_sample_annotation.txt) Gene expression data from CD44+/CD24- cells sorted by flow cytometry (GSE7513.gct) Human...

  15. Multiclass cancer diagnosis using tumor gene expression signatures

    10 Nov 2014 | Downloads

    Experiment Description:    The optimal treatment of patients with cancer depends on establishing accurate diagnoses by using a complex combination of clinical and histopathological data. In some instances, this task is difficult or impossible because of atypical clinical...

  16. Analysis, integration and visualization of DNA methylation sequencing data

    07 Nov 2014 | Presentations | Contributor(s): Maureen Sartor

    Integrative epigenomic/genomic profiling and biomarker discovery of HPV+ and HPV- squamous cancers.

  17. Summarization of Big Data

    07 Nov 2014 | Presentations | Contributor(s): Jeffrey A. Blimes

    All about assay selection...

  18. Biomedical Evidence Graph

    03 Oct 2014 | Presentations | Contributor(s): Josh Stuart

  19. Tools to Analyze Morphology and Spatially Mapped Molecular Data

    03 Oct 2014 | Presentations | Contributor(s): Joel Saltz

  20. Integrated analysis of breast cancer cell lines reveals unique signaling pathways

    16 Sep 2014 | Publications | Contributor(s): Laura M Heiser, Nicholas J Wang, Carolyn L Talcott, Keith R Laderoute, Merrill Knapp, Yinghui Guan, Zhi Hu, Safiyyah Ziyad, Barbara L Weber, Sylvie Laquerre, Jeffrey R Jackson, Richard F Wooster, Wen Lin Kuo, Joe W Gray, Paul T Spellman

    AbstractBackgroundCancer is a heterogeneous disease resulting from the accumulation of genetic defects that negatively impact control of cell division, motility, adhesion and apoptosis. Deregulation in signaling along the EgfR-MAPK pathway is common in breast cancer, though the manner in which...