CEINT's NanoPHEAT Project : Integrating Exposure and Toxicity Data to Build Risk Forecasting Tools
16 Apr 2020 | Contributor(s): Mark Wiesner, Jaleesia Amos
The NanoPHEAT tool (Nano Product Hazard and Exposure Assessment Tool) is built to compile dose-response curves from literature, including hundreds of papers, and calculates the estimated exposure to nanoparticles as released from real products, based on some in-house experimental values that we...
Jaqpot - An open-source web platform for creating, using, testing and sharing predictive models in nano-informatics
20 Jun 2019 | Contributor(s): Haralambos Sarimveis
Nano WG June 20, 2019Computational models that predict physicochemical properties, biokinetics or adverse biological effects of Engineered Nanomaterials (ENMs) are becoming increasingly important to support risk assessment and safety-by-design. This is primarily due to cost-saving and...
Transitioning to Predictive Analysis for Nanoparticle Biocorona Studies
14 May 2019 | Contributor(s): Korin Wheeler
Nano WG April 18, 2019: Proteins adsorbed to nanomaterials in a biological environment mediate cellular recognition, uptake, and toxicity of nanomaterials. Here, Dr. Korin Wheeler presents the development of experimental methods to characterize this population of proteins (also...
The history of chemical information and the materials of the future
25 Apr 2019 | Contributor(s): Evan Hepler-Smith
Techniques, technologies, cultures, and infrastructures of information management played a central role in the development of the modern chemical sciences and the global chemicals industry since the late 19th century. Chemical databases and analytical techniques that privileged abstract,...
FAIR for NanoSafety: where do we stand?
05 Apr 2019 | Contributor(s): Egon Willighagen
Nano WG April 4, 2019 Findable, Accessible, Interoperable, Reusable (FAIR) sharing of nanosafety data.
Dataset Curation, Assessment of their Quality, and Prediction Model Developments for Safe and Sustainable Nanotechnology (S2NANO)
29 Nov 2018 | Presentations | Contributor(s): Tae Hyun Yoon
Nano WG November 29, 2018: Tae Hyun Yoon, Prof./CEO/Ph.D., Yoon Idea Lab. Co. Ltd. & Hanyang University In this presentation, I will introduce our recent research outcomes from S2NANO: PredictNANO project, which aimed to bridge the nanosafety knowledge gaps between R&D...
NanoInformatics Knowledge Commons Curation Team: Building the Data Dictionary to Enrich Data Curation
11 Jul 2018 | Presentations | Contributor(s): Jaleesia Amos, Yuan Tian, Mervi Heiskanen
Nano WG Presentation, May 31st, 2018 Organized storing of data using informed-decision making to determine what information should be curated, when data curation is complete, and how to identify high-quality data. Purpose of NIKC structure & curation process: tell the story of...
Overview of the NCI Cancer Research Data Commons, Genomic Data Commons (GDC), and NCI Cloud Resources
07 Jun 2018 | Presentations | Contributor(s): Tanja Davidsen, Mervi Heiskanen
Nano WG presentation, June 7, 2018 by Tanja Davidsen, NCI CBIIT The Cancer Research Data Commons (CRDC) and NCI Cloud Resources overview.
Dissolution as a Paradigm in Regulating Nanomaterials
16 Aug 2017 | Presentations | Contributor(s): Frederick C. Klaessig
Nano WG presentation, August 10, 2017 Themes: • Dissolution as a decision criterion • Analogies to ζ-potential & VSSA • Relation to nanoform & nanoscale form • Dissolution kinetics and artifacts • ASTM particle ontology & Nanoinformatics Roadmap...
15 Aug 2017 | Publications | Contributor(s): Stephanie Morris
Collated tweets from workshop and networking reception.
05 Jul 2017 | Presentations | Contributor(s): Stephanie Morris, Mervi Heiskanen
General Overview of the caNanoLab data portal: data submission workflow, collaboration features, data sharing and working with Journals and PubMed to share information about data submissions.
NANOANALYTICS OF EXTRACELLULAR VESICLES – Standards for isolation, characterization and reporting
26 May 2017 | Presentations | Contributor(s): Shivani Sharma
Nano WG presentation on May 25, 2017. Presentation by Dr. Shivani Sharma, Associate Director of the Nano Pico Characterization Lab, UCLA. Nanoscale characterization of exosomes and their use disease biomarkers and drug delivery agents
European Chemical Agency's work to implement REACH regulation for nanomaterials
04 May 2017 | Presentations | Contributor(s): Frank Le Curieux
Nano WG presentation on May 4, 2017. REACH = Registration, Evaluation, Authorisation (& restriction) of Chemicals aims to ensure a high level of protection of human health and the environment while enhancing competitiveness and innovation. Nano materials are covered by...
Human Disease Ontology
21 Sep 2016 | External Applications | Contributor(s): Lynn Schriml
The Disease Ontology has been developed as a standardized ontology for human disease, since 2003, with the purpose of providing the biomedical community with manual curated, consistent, reusable and sustainable descriptions of human disease terms, phenotype characteristics and related...
Integrative Cancer Biology Program Datasets
26 Apr 2016 | Series | Contributor(s): Jonathan Bistline, Michael Reich
The NCI-ICBP promotes an integrative/systems approach to the study of cancer biology. The Program encourages scientists to study cancer as a complex biological system. Information gained from these studies are used to build reliable and testable predictive computation models of cancer processes...
Summary of the 2015 Epigenetic Engineering for Cancer Workshops
22 Dec 2015 | Publications | Contributor(s): Tony Dickherber
This document provides a general summary of the 2 virtual workshops held in Fall of 2015 to explore the suitability of epigenetic engineering tools to specifically modify epigenetic loci to study and/or treat cancer.
Community Health Worker Genetics Education Needs Assessment
23 Nov 2015 | Downloads | Contributor(s): Andria Reyes, Manuela Orjuela, Karen Schmitt, Andria Reyes, Grace Hillyer, Stephen Emerson
Our overarching goal is to develop and establish a cancer genetics curriculum that is pertinent, culturally sensitive and understandable by a community population who is not English dominant and of a lower literacy level than that of the general New York City population. The curriculum will teach...
Breast Cancer Crossword
20 Nov 2015 | Teaching Materials | Contributor(s): Katelyn Schifano
This crossword is designed for use in social media as well as patient waiting areas.
"Show me the data!" Practical solutions to interactive visual analysis for big data.
18 Sep 2015 | Presentations | Contributor(s): Samuel Payne
Nano WG September 10, 2015.Intuitive data visualization is critical for biomedical data analysis; especially essential is the ability for non-computational scientists to productively browse the data and apply their domain knowledge. We present Active Data Biology, a web-based visual...
Screening for Small Molecules: Target Discovery Against miRNAs for Breast Cancer Treatment
18 Aug 2015 | Presentations | Contributor(s): Odemaris Narvaez del Pilar
Breast cancer is one of the leading causes of cancer related deaths and morbidity among women worldwide. Identifying new targets and developing new therapies is very important in order to improve patient outcomes and minimize this health burden. MicroRNAs, a type of non-coding RNA, are potential...