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  1. Next-Generation Clustered Heat Maps (NG-­CHM)

    07 Oct 2015 | Contributor(s): Weinstein John, Bradley Broom

    Clustered Heat Maps (CHMs) have been referred to as the ubiquitous visual icons of post-genomic biology -- the most frequent type of visualization for large molecular profiling databases. However, “traditional” CHMs are static images -- a serious limitation. Accordingly, we have now...

  2. Open source diffusion MRI technology for brain cancer research

    07 Oct 2015 | Contributor(s): Lauren O\'Donnell

    Using measurements of water diffusion, dMRI can give unique insights into the microstructure and cellular orientation of tissues. There is a growing awareness in the neurosurgery community that diffusion models must move beyond the current clinical standard of the diffusion tensor for better...

  3. Pathology Image Informatics Platform for visualization, analysis and management

    07 Oct 2015 | Contributor(s): Metin Gurcan, Anant Madabhushi, Anne Martel

    This multi-institutional proposal seeks to expand on an existing, freely available pathology image viewer (Sedeen Image Viewer) to create a pathology informatics platform (PIIP) for managing, annotating, sharing, and quantitatively analyzing digital Pathology Imaging (DPI) data. Sedeen has become...

  4. Screening for Small Molecules: Target Discovery Against miRNAs for Breast Cancer Treatment

    18 Aug 2015 | Contributor(s): Odemaris Narvaez del Pilar

    Breast cancer is one of the leading causes of cancer related deaths and morbidity among women worldwide. Identifying new targets and developing new therapies is very important in order to improve patient outcomes and minimize this health burden. MicroRNAs, a type of non-coding RNA, are potential...

  5. The history of chemical information and the materials of the future

    25 Apr 2019 | Contributor(s): Evan Hepler-Smith

    Techniques, technologies, cultures, and infrastructures of information management played a central role in the development of the modern chemical sciences and the global chemicals industry since the late 19th century. Chemical databases and analytical techniques that privileged abstract,...

  6. Transitioning to Predictive Analysis for Nanoparticle Biocorona Studies

    14 May 2019 | Contributor(s): Korin Wheeler

    Nano WG April 18, 2019: Proteins adsorbed to nanomaterials in a biological environment mediate cellular recognition, uptake, and toxicity of nanomaterials. Here, Dr. Korin Wheeler presents the development of experimental methods to characterize this population of proteins (also...