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  1. Accelerating Nanotech Innovations Through a Safer-By-Design Approach, Safer Nanomaterials School

    14 May 2019 | Contributor(s): Philippe Sabatier

    Nano WG May 9, 2019European Scientific Institute (ESI) Safer Nanomaterials School Introduction.

  2. Baylor Residual breast cancer

    13 Nov 2014 | Downloads | Contributor(s): Creighton C, Lewis M, Chang J, Jonathan Bistline

    Residual breast cancers after conventional therapy display mesenchymal as tumor-initiating features.  There are four (4) files included in this study: Sample Annotation (combined_sample_annotation.txt) Gene expression data from CD44+/CD24- cells sorted by flow cytometry (GSE7513.gct) Human...

  3. Breast Cancer Crossword

    20 Nov 2015 | Teaching Materials | Contributor(s): Katelyn Schifano

    This crossword is designed for use in social media as well as patient waiting areas.

  4. caNanoLab: data sharing to expedite the use of nanotechnology in biomedicine

    13 Dec 2013 | Publications | Contributor(s): Sharon Gaheen, George W Hinkal, Stephanie A Morris, Michal Lijowski, Mervi Heiskanen, Juli Klemm

    The use of nanotechnology in biomedicine involves the engineering of nanomaterials to act as therapeutic carriers, targeting agents and diagnostic imaging devices. The application of nanotechnology in cancer aims to transform early detection, targeted therapeutics and cancer prevention and...

  5. Development of natural language processing tools for nanoparticle design

    05 Mar 2019 | Presentations | Contributor(s): Nastassja Lewinski

    Nano WG February 28, 2019: In this presentation, an introduction to the application of natural language processing techniques to nanotechnology data will be discussed.  Natural language processing tools can aid in the automatic categorization, extraction, and analysis of data from...

  6. Development of Targeted Nanomedicines via Machine Learning Processes

    05 Mar 2019 | Presentations | Contributor(s): Daniel Heller

    Nano WG February 21, 2019Description: We are using data science to facilitate the development of nanoparticle drugs incorporating kinase inhibitors with diverse chemical structures. Doing this work inspired us to bring together the nanoinformatics community...

  7. Integrated analysis of breast cancer cell lines reveals unique signaling pathways

    16 Sep 2014 | Publications | Contributor(s): Laura M Heiser, Nicholas J Wang, Carolyn L Talcott, Keith R Laderoute, Merrill Knapp, Yinghui Guan, Zhi Hu, Safiyyah Ziyad, Barbara L Weber, Sylvie Laquerre, Jeffrey R Jackson, Richard F Wooster, Wen Lin Kuo, Joe W Gray, Paul T Spellman

    AbstractBackgroundCancer is a heterogeneous disease resulting from the accumulation of genetic defects that negatively impact control of cell division, motility, adhesion and apoptosis. Deregulation in signaling along the EgfR-MAPK pathway is common in breast cancer, though the manner in which...

  8. Integrative Cancer Biology Program Datasets

    26 Apr 2016 | Series | Contributor(s): Jonathan Bistline, Michael Reich

    The NCI-ICBP promotes an integrative/systems approach to the study of cancer biology. The Program encourages scientists to study cancer as a complex biological system. Information gained from these studies are used to build reliable and testable predictive computation models of cancer processes...

  9. LBL ICBP50 integrative genomic data

    13 Nov 2014 | Downloads | Contributor(s): Joe Gray, Jonathan Bistline

    From Joe Gray, Lawrence Berkeley National Laboratory.  There are seventeen (17) files in this study: Affymetrix U133A gene expression data (icbp_u133a.gct) Affymetrix U133A gene expression data (ICBP_U133a.zip) Affymetrix splice junction exon-exon data (ICBP_Junction.zip) Affymetrix...

  10. NCI Alliance for Nanotechnology in Cancer, and caNanoLab: A Data Repository for Cancer Nanomedicines

    27 Nov 2018 | Presentations | Contributor(s): Luisa Russell, Mervi Heiskanen

    Nano WG presentation November15, 2018 NCI Alliance for Nanotechnology in Cancer –Structure–Achievements–Scientific FocuscaNanoLab–Intro to Platform–Data Curation–User Statistics–Future Directions

  11. Screening for Small Molecules: Target Discovery Against miRNAs for Breast Cancer Treatment

    18 Aug 2015 | Presentations | Contributor(s): Odemaris Narvaez del Pilar

    Breast cancer is one of the leading causes of cancer related deaths and morbidity among women worldwide. Identifying new targets and developing new therapies is very important in order to improve patient outcomes and minimize this health burden. MicroRNAs, a type of non-coding RNA, are potential...