Integrated analysis of breast cancer cell lines reveals unique signaling pathways

16 Sep 2014 | Contributor(s): Laura M Heiser, Nicholas J Wang, Carolyn L Talcott, Keith R Laderoute, Merrill Knapp, Yinghui Guan, Zhi Hu, Safiyyah Ziyad, Barbara L Weber, Sylvie Laquerre, Jeffrey R Jackson, Richard F Wooster, Wen Lin Kuo, Joe W Gray, Paul T Spellman

AbstractBackgroundCancer is a heterogeneous disease resulting from the accumulation of genetic defects that negatively impact control of cell division, motility, adhesion and apoptosis. Deregulation in signaling along the EgfR-MAPK pathway is common in breast cancer, though the manner in which...

Integrative Cancer Biology Program Datasets

26 Apr 2016 | Series | Contributor(s): Jonathan Bistline, Michael Reich

The NCI-ICBP promotes an integrative/systems approach to the study of cancer biology. The Program encourages scientists to study cancer as a complex biological system. Information gained from these studies are used to build reliable and testable predictive computation models of cancer processes...

Introduction to the Trinity Cancer Transcriptome Analysis Toolkit

05 Feb 2015 | Teaching Materials | Contributor(s): Brian Haas, Aviv Regev, Bill Barnett

This short video provides an overview of our ITCR-funded effort to leverage RNA-Seq and de novo transcriptome assembly to assist researchers in studying cancer transcriptomes.  Visit our NCGAS Trinity/Galaxy portal to access these compute...

LBL ICBP50 integrative genomic data

13 Nov 2014 | Downloads | Contributor(s): Joe Gray, Jonathan Bistline

From Joe Gray, Lawrence Berkeley National Laboratory.  There are seventeen (17) files in this study: Affymetrix U133A gene expression data (icbp_u133a.gct) Affymetrix U133A gene expression data (ICBP_U133a.zip) Affymetrix splice junction exon-exon data (ICBP_Junction.zip) Affymetrix...

Multiclass cancer diagnosis using tumor gene expression signatures

10 Nov 2014 | Downloads

Experiment Description:    The optimal treatment of patients with cancer depends on establishing accurate diagnoses by using a complex combination of clinical and histopathological data. In some instances, this task is difficult or impossible because of atypical clinical...

NANOANALYTICS OF EXTRACELLULAR VESICLES – Standards for isolation, characterization and reporting

26 May 2017 | Presentations | Contributor(s): Shivani Sharma

Nano WG presentation on May 25, 2017. Presentation by Dr.  Shivani Sharma, Associate Director of the Nano Pico Characterization Lab, UCLA. Nanoscale characterization of exosomes and their use disease biomarkers and drug delivery agents

NCIP Hub QIN Workshop - March 3, 2015

19 Mar 2015 | Presentations | Contributor(s): Michael McLennan

Mike McLennan, director of HUBzero, presented an overview of basic NCIP Hub functionality to the QIN group on March 3, 2015. The presentation included an overview of the "hub" and HUBzero, and touched upon functionality such as projects, groups, resources and information sharing. The...

NCIP Hub: Collaboration Tool for NCI Affiliated Programs and Investigators

16 Nov 2018 | Presentations | Contributor(s): Mervi Heiskanen, Aparna Vinodh

NCIP Hub overview and CRCHD PACHE Hub demonstration.

pRainBow optical barcoding library

14 Aug 2014 | Reagents | Contributor(s): Andries Zijlstra

Note: this is a work in progress. About: pRainBow is a library of lentiviral vectors designed to allow for fluorescent labeling of cells with one of 7 distinct fluorescent proteins. Composition: How to obtain: How to cite: Other information:Good global...

QIBA Status

21 Apr 2014 | Presentations | Contributor(s): Daniel Sullivan, Vyshak Chandra

Status and potential for further collaboration with RSNA QIBA

QIN HUBzero update

28 Oct 2013 | Teaching Materials | Contributor(s): Jayashree Kalpathy-Cramer

presentation for the QIN EC meeting 10/21/2013

QIN Tools Inventory Summary

15 Oct 2014 | Teaching Materials | Contributor(s): Andrey Fedorov

QIN Tools survey has been conducted in two iterations starting from the Spring 2014 [1]. In the beginning of Summer 2014, a revised version of the survey has been released [2]. The results of the survey are available at [3], and also include the analysis of other data sources (such as “QIN...

Quantitative Image Informatics for Cancer Research (QIICR)

04 Apr 2014 | Presentations | Contributor(s): Andrey Fedorov, Ron Kikinis

Quantitative Imaging Network (QIN) in China

18 Apr 2014 | Presentations | Contributor(s): Yan Kang

A presentation on challenges & opportunities for QIN in China

Quantitative Imaging Network(QIN) BIDS Related Tools

27 Oct 2014 | Downloads | Contributor(s): Andrey Fedorov, Thomas Casavant

An inventory of the software tools used by the QIN sites to facilitate collaborative efforts such as sharing of analysis results and software tools.

Rationale for Creating an International Forum and NCI Funding Opportunities

18 Apr 2014 | Presentations | Contributor(s): Larry Clarke

The topic here is the creation of research networks and their value to cancer research.The Cancer Imaging Program, is administering several research networks. This presentation on the creation and value of two of them (The Network for Translational research or NTR, and the Quantitative Imaging...

Report to the DICOM Standards Committee - December 4, 2015

10 Dec 2014 | Downloads | Contributor(s): Joseph Kalen

Screening for Small Molecules: Target Discovery Against miRNAs for Breast Cancer Treatment

18 Aug 2015 | Presentations | Contributor(s): Odemaris Narvaez del Pilar

Breast cancer is one of the leading causes of cancer related deaths and morbidity among women worldwide. Identifying new targets and developing new therapies is very important in order to improve patient outcomes and minimize this health burden. MicroRNAs, a type of non-coding RNA, are potential...