Integrated analysis of breast cancer cell lines reveals unique signaling pathways
16 Sep 2014 | Contributor(s): Laura M Heiser, Nicholas J Wang, Carolyn L Talcott, Keith R Laderoute, Merrill Knapp, Yinghui Guan, Zhi Hu, Safiyyah Ziyad, Barbara L Weber, Sylvie Laquerre, Jeffrey R Jackson, Richard F Wooster, Wen Lin Kuo, Joe W Gray, Paul T Spellman
AbstractBackgroundCancer is a heterogeneous disease resulting from the accumulation of genetic defects that negatively impact control of cell division, motility, adhesion and apoptosis. Deregulation in signaling along the EgfR-MAPK pathway is common in breast cancer, though the manner in which...
Overview: The HUBzero Platform for Scientific Collaboration
18 Dec 2013 | Presentations | Contributor(s): Michael McLennan
This web site was created using a collaborative infrastructure called HUBzero, developed by Purdue University. HUBzero is the basis of nanoHUB.org and more than 50 other sites covering a wide range of scientific disciplines, including bio-fuels, microelectromechanical systems, cancer research,...