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NCL Method STE-1.4

By Barry Neun, Marina Dobrovolskaia

Detection and Quantification of Gram-Negative Bacterial Endotoxin Contamination in Nanoparticle Formulations Using the Kinetic Chromogenic LAL Assay

Listed in Datasets | publication by group NCL Protocols

Version 1.0 - published on 14 Jun 2021 doi:10.17917/B6HB-C950 - cite this

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This document describes a protocol for a quantitative detection of Gram-negative bacterial endotoxin in nanoparticle preparations using a kinetic chromogenic Limulus Amebocyte Lysate (LAL) assay. The protocol is based on the USP standard 85 “Bacterial endotoxin test” [1].

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