Profile

• Organization

  Frederick National Laboratory

  
  
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• Website

  http://ncifrederick.cancer.gov/atp/proteins-and-proteomics/protein-expression-laboratory/

  
  
• Reason

  (not set)

  
  
• Interests

  1. DNA recombination
  2. Gateway cloning
  3. molecular biology
  4. protein-DNA interactions
  5. protein production
  6. structural biology

  
  
• Biography

  Dr. Esposito is currently the Director of the Protein Expression Laboratory (PEL) at the Frederick National Laboratory for Cancer Research (FNL) in Maryland. The staff of the PEL generate proteins of interest to investigators at the National Cancer Institute, and are helping to lead the new FNL national mission to target KRAS-driven cancers. Prior to his role as director, Dr. Esposito led the Clone Optimization Group in the PEL for 9 years and was responsible for the generation of over 15,000 expression clones, 400 new expression vectors, and several technological innovations in protein expression. Dr. Esposito received his BA in Chemistry at La Salle University in Philadelphia, and his PhD in Biochemistry at the Johns Hopkins University Bloomberg School. Dr. Esposito previously worked for Life Technologies, where he helped to develop the Gateway recombinational cloning system.