NCI / FNL Workshop on RAS Synthetic Lethality
25 Feb 2014 | Downloads | Contributor(s): James Hartley
"Synthetic lethality" is a term of classical genetics that refers to a combination of defective genes that is deadly together (synthetically, i.e., when both genes A and B are inactivated) but not when one or the other (A or B) is inactive. It is known that animal models of cancer can be...