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Fourth ISC Workshop on HPC Applications in Precision Medicine – Virtual (Rescheduled from 2020)

July 2, 2021 | Virtual

Conference Website:

Due to COVID-19 pandemic, the workshop will be virtual.

Call for Extended Abstracts Submission Site:

Abstract Submission Deadline: May 1, 2021


Important Dates


Abstract Submission Deadline May 1, 2021
Notification of Acceptance May 6, 2021
Early Bird Registration Rate Deadline May 6, 2021
Workshop July 2, 2021

Program Overview

High performance computing has become central to the future success of precision medicine. Catalyzed by the dramatic increase in the volume of research and clinical data available through sequencing and advanced imaging techniques, clinical data available through medical records and mobile health devices, research data from automated platforms, combined with molecular simulations and the rapid adoption of deep learning approaches has created a convergence shaping the frontiers of computing and precision medicine. New approaches to drug discovery, data sharing, aggregation and safeguards, use of machine learning models in research and clinical contexts has identified new challenges and opportunities in these rapidly evolving frontiers. The growth of opportunities to incorporate HPC in precision medicine applications continues to accelerate, exemplified by a very successful EU funded CompBioMed Conference held in September 2019 and pervasive presence of advanced computing applications at the recent SC20 conference, including the more than 130 people at the virtual Sixth Computational Approaches for Cancer workshop.

The workshop provides an opportunity to address key challenges. Synergies among experiments and clinical applications and theory in precision medicine research are often complicated by the lacking availability of primary data. Given the growing use of predictive models in multiple forms, especially in the context of deep learning and AI, large volumes of reliable and well annotated information are needed to establish a ground truth for training, for evaluation and even for validation of models. During the workshop, connections will be made across the communities, discussing platforms and possible ongoing solutions to facilitate development, referencing and exchange of experimental data and computational results. A special theme for this year's workshop will be HPC and Biomedical Digital Twins.


Workshop Motivation

High-performance computing has become integral to the future success of precision medicine. Through advanced technologies such as next generation sequencing, advanced imaging, and mobile health monitoring, multiple new approaches are in development to ascend to the potential for precision medicine prevention, detection, diagnostics, treatment and surveillance. Coupled with the rapidly developing capabilities in artificial intelligence, advances in data aggregation, sharing and security, and emerging predictive and prescriptive models, a compelling frontier emerges where high-performance computing enables important improvements in patient outcomes and new innovations accelerating towards a precision medicine future. The HPC Applications in Precision Medicine workshop aims to bring together the breadth of communities including clinical, pharmaceutical, mobile health, health information systems, data security, computational and data science domains to share experiences, examine current challenges, and explore future opportunities for high-performance computing enabled applications in precision medicine. In the workshop, we bring together individuals from across the globe with these interests and more to share insights, experiences and showcase new capabilities in this rapidly evolving field.


Target Audience

The workshop is expected to attract those researchers, thought leaders, clinicians, data engineers and scientists, health information leaders, computational innovators across academia, industry and non-profit organizations globally to identify challenges and opportunities in computational precision medicine, sharing both common and unique perspectives to seed future collaborative solutions. Leaders in large-scale computing, deep learning, modeling and simulation join the community with glimpses into the future. The workshop also draws individuals from the breadth of precision medicine application areas spanning research to clinical application in areas including drug discovery, preclinical validation, diagnostics, health monitoring, precision biomarker development, prevention and early detection, treatment determination and population studies, interested in the computational and data challenges and opportunities created in precision and predictive medicine.


Workshop Organizing Committee

The initial workshop organizing committee has spearheaded the identification of presenters from both Europe, US and Asia. The committee was strongly supported by colleagues in identifying the slate of presenters for past workshops and has support for the same in developing the program for the 2021 workshop.

Marco Berghoff – Karlsruhe Institute of Technology

Stephen Litster – Amazon Web Services

Jan Nygard – Cancer Registry of Norway

Eric Stahlberg – Frederick National Laboratory for Cancer Research

Thomas Steinke – Zuse Institute Berlin

Lynn Borkon – Frederick National Laboratory for Cancer Research (

Petrina Hollingsworth – Frederick National Laboratory for Cancer Research (

Created by Petrina Hollingsworth Last Modified Tue April 20, 2021 1:14 pm by Petrina Hollingsworth